What is the major histocompatibility complex

What is major histocompatibility complex?

http://wiki.answers.com/Q/What_is_major_histocompatibility_complex

The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates. It is the most gene-dense region of the mammalian genome and it plays an important role with the immune system, autoimmunity, and…

What is the “major histocompatibility complex (MHC)” ex…?

http://answers.yahoo.com/question/index?qid=20090115093927AAJk9bF

MHC are a group of linked loci (genes) located on chromosome 6. Their gene products are cell-surface MHC antigens which are referred to as HLA. MHC is subdivided into 3 types : MHC I, II and III. MHC I gene products are HLA-A, HLA-B and HLA…

Are major histocompatibility complex molecules involved in the su…?

http://www.ncbi.nlm.nih.gov/pubmed/2534796

Grandjean I, Duban L, Bonney EA, Corcuff E, Di Santo JP, Matzinger P, Lantz O. J Exp Med. 2003 Oct 6; 198(7):1089-102. Epub 2003 Sep 29.

Related Questions Answered on Y!Answers

what does the major histocompatibility complex have 2 do with sexual attraction?

Q: what does the major histocompatibility complex have 2 do with sexual attraction

A: since the mhc are the genes you have to code for the set of exterior proteins that allow your cells to identify itself to each other the theory is thus:viruses and bacteria may in order to to infect your cells need to be compatible with your mhc.therefore the more different mhc the betterhence there may be factors that allow us to better discern who has a more different mhc from us. The current theory is these factors are mainly ‘smell’ based. if they do they’re more attractive and we pick them over someone whose more similar to us.They did a study where they had women smell t-shirts that various guys had spent the night sleeping in. They rated what they were attracted to more and less. Consistently it proved they were attracted to t-shirts from males of different races than their own. No one liked mexicans ’cause how can you? :PInterestingly enough, when they tested pregnant women they found proportionally the opposite, which makes sense cause if one’s pregnant her (his? O.o) baby is going to be guaranteed to smell something like her race and hence her attention is off the male and onto the baby who would mhc-wise be more like her than her lover would be like her.

What is the “major histocompatibility complex (MHC)” exactly ?

Q: Is it a molecule by itself that presents antigen?or is it present on the surface of antigen presenting cells like dendritic cells..etcand why they are called HLA(human leukocyte antigen) in humans?what’s thier relation to leukocytes?

A: MHC is an antigen-presenting protein complex that is found on the surface of cells. HLA is another name for MHC.

Why are T cells that do not react to major histocompatibility complex killed off?

Q:

A: because T cells respond to antigenic peptides presented in the context of MHC class I molecules. Without appropriate interaction with MHC then the reconition and subsequent cell signaling and activation cannot occur.